Ketamine treatment
Ketamine has been studied for treatment-resistant depression. A 2023 randomized trial compared IV ketamine with ECT in adults with nonpsychotic treatment-resistant major depression; its findings do not apply automatically to psychotic depression, every patient or every route. FDA-approved Spravato is esketamine, a different medication and administration program.
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New York County · New York
No clinic is currently listed inside Manhattan. The closest listed option is 0.3 straight-line miles away, in New York.
Independent directory · confirm services and addresses directly. Educational information, not medical advice.
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Manhattan, the densely populated heart of New York City and coextensive with New York County, is a major global hub for medical research and specialized healthcare. Residents and visitors navigating the borough's complex street grid and extensive public transit system have access to several local clinics offering modern psychiatric interventions, including ketamine therapy and Spravato for treatment-resistant conditions.
Patients in Manhattan can find several directory-listed facilities providing these services. Clinics physically located in the borough include Village TMS | Licensed TMS Therapy + Ketamine Provider, which lists Spravato treatment, and Keta Medical Center - Midtown | IV Ketamine and Spravato, offering IV ketamine and Spravato. Other established facilities are NY Ketamine Infusions for IV and Spravato care, Hudson Mind for Spravato treatment, and Journey Clinical - Midtown Manhattan Clinic, which also provides in-clinic Spravato.
Treatment schedules vary by clinic and treatment type, so plan transportation for each visit. Distances below are straight-line miles from Manhattan.
0.3 miles away · New York
123 West 86th Street, Suite g, New York
4.8(20 Google reviews)
Keta Medical Center | Ketamine Therapy | Spravato is listed in New York, New York. The listed appointment address is 123 W 86th St Ste g, New York, NY 10024, USA. Confirm the current location with the practice before travelling.
0.7 miles away · New York
7 West 96th Street, Apt 1h, New York
4.6(41 Google reviews)
Keta Medical Center | Ketamine Therapy | Spravato is listed in New York, New York. The listed appointment address is 7 W 96th St Apt 1h, New York, NY 10025, USA. Confirm the current location with the practice before travelling.
1 miles away · New York
17 East 97th Street, 1C, New York
5.0(2 Google reviews)
Creative Healing Psychiatry | David H. Lifschutz, MD | Ketamine and Psychotherapy is listed in New York, New York. The listed appointment address is 17 E 97th St 1C, New York, NY 10029, USA. Confirm the current location with the practice before travelling.
1.3 miles away · New York
30 East 60th Street, 1002, New York
3.9(9 Google reviews)
Ember Health - Upper East Side | IV Ketamine Treatment for Depression NYC is listed in New York, New York. The listed appointment address is 30 E 60th St 1002, New York, NY 10022, USA. Confirm the current location with the practice before travelling.
1.3 miles away · New York
119 West 57th Street, Suite 1006, New York
Treatment information
1.3 miles away · New York
425 East 86th Street, Apartment 1a, New York
5.0(118 Google reviews)
Fountain Health NYC | Ketamine Therapy, Brain & Mental Health is listed in New York, New York. The listed appointment address is 425 East 86th St Apt 1a, New York, NY 10028, USA. Confirm the current location with the practice before travelling.
Manhattan clinics offer various modalities, including the FDA-approved Spravato (esketamine) nasal spray for specific types of depression. Many clinics also provide off-label intravenous (IV) or intramuscular (IM) ketamine infusions. Patients should consult with a specialized psychiatrist to determine which formulation is medically appropriate for their specific psychiatric condition.
No, clinics generally do not permit patients to travel home alone via the subway or bus system following treatment due to the risk of lingering sedation and dissociation. You must be escorted by a responsible adult, such as a friend or family member, usually via taxi or a rideshare.
Insurance may cover FDA-approved Spravato for treatment-resistant depression, pending prior authorization. However, off-label IV or IM ketamine treatments are typically not covered by insurance and require out-of-pocket payment. Always verify benefits with your insurance provider and the clinic beforehand to understand your financial responsibilities.
Spravato sessions require a mandatory post-administration observation period of at least two hours in a certified clinical setting. Intravenous (IV) ketamine appointments generally last a similar duration, accounting for preparation time, the active infusion, and a brief recovery period before you are safely discharged to your escort.
Telehealth may be utilized for initial psychiatric evaluations, treatment planning, and follow-up consultations. However, the actual administration of Spravato and supervised in-clinic ketamine treatments must always be conducted in person to ensure patient safety and proper medical monitoring throughout the duration of the session.
If you are in immediate distress or facing a psychiatric emergency, do not wait for a scheduled clinic appointment. Call or text the 988 Suicide & Crisis Lifeline at 988, or call 911 for urgent medical assistance. Both of these essential crisis services operate 24/7.
Costs, coverage & aftercare
IV, IM and compounded ketamine for psychiatric conditions are off-label; many programs are self-pay. Ask about assessment, medication, administration, monitoring, therapy and maintenance charges separately. We do not assume a statewide price.
Spravato is FDA-approved esketamine, not the same as ketamine infusions. Coverage is not guaranteed. Check eligibility, prior authorization, network status, drug and visit charges, deductibles and copays with your insurer and clinic.
Spravato requires a certified healthcare setting and monitoring for at least two hours. Arrange transport home; do not drive until the next day after restful sleep. For other ketamine treatments, follow your clinician's instructions. Follow-up and maintenance depend on response and tolerability.
Ask who manages your medications, how your usual clinician will receive updates, and whom to contact between visits. Neither a shortage designation nor local depression statistics show that ketamine is appropriate or effective for you. Consult a licensed physician.
Use these questions when you call or book a consultation with any Manhattan provider.
Ask whether a physician, psychiatrist or anesthesiologist oversees each session and who you can reach afterward.
A good clinic reviews your history, medications, blood pressure and past treatments before recommending ketamine.
Look for continuous vital-sign monitoring and a calm, private recovery space.
IV infusions, Spravato® nasal spray, IM or sublingual options suit different goals and budgets.
Ask how the clinic coordinates with your therapist or offers integration support between sessions.
Request a written estimate for the first series and any maintenance sessions before you start.
Ratings come from public Google reviews and change over time. Listing order is not a medical recommendation.
Many patients travel a short distance for a clinic that fits their needs. Explore ketamine care in these nearby communities.
Browsing a wider area? See every clinic in New York County
Conditions Ketamine treats, county-wide options and guides written for New York patients.